Tolerability is the ability to take a medication as recommended without experiencing side effects that cause you to stop taking it or take a reduced dose. Because MBC treatment is lifelong, ways to improve tolerability are very important. Many clinical trials study new ways to improve the tolerability of MBC treatment.
Read below for ways that make MBC treatment easier to tolerate, such as changing the dose and changing the administration, which is how a medication is given.
Current Research
- Breast Cancer Research Foundation: Changing the dose of capecitabine (Xeloda®) decreases toxicity while maintaining anti-cancer activity (scroll to X-7/7 study: Practice-changing strategy for oral chemotherapy)
- Breastcancer.org: Paclitaxel (Taxol®) by mouth was more effective than by IV and could allow fewer visits to the doctor
- Breastcancer.org: Trastuzumab, pertuzumab, and hyaluronidase (Phesgo®) by injection allows faster administration than by IV for people with HER2-positive MBC
MBC Clinical Trials
- Metastatic Trial Search: Trials for Managing Side Effects
Last Modified on September 26, 2023