We added the following clinical trials to Metastatic Trial Search for December 2025. To see all clinical trials, please visit Metastatic Trial Search.

ER/PR Positive Trials

• GTAEXS617 for Advanced HR+ HER2- Breast Cancer

HER2 Positive Trials

• Disitamab Vedotin Antibody-Drug Conjugate for Advanced HER2+, HER2 Low, or HER2 Ultralow Breast Cancer

Triple Negative Trials

• BMS-986507 for Advanced Triple Negative or ER Low Breast Cancer
• LY4175408 for Advanced Triple Negative Breast Cancer

Other Stage IV Trials

• Education to Improve Early Advance Care Planning for Adolescents and Young Adults With Brain Metastases
• DSB2455 PARP1 Inhibitor for Brain Metastasis

Last Modified on December 1, 2025