If you are considering enrolling in a clinical trial or are reading clinical trial results, you may see unfamiliar terms about different types of clinical trials. This month, we continue our series about clinical trial terms by discussing basket trials, umbrella trials, and tumor agnostic trials. Tumor agnostic drugs are often studied in basket trials. Tumor agnostic trials are also called solid tumor trials.
Click the links below to learn more about these terms and find these types of clinical trials.
Umbrella and Basket Trials
- Roche (video): Umbrella trials enroll patients with the same cancer and give them personalized treatments, and basket (or bucket) trials treat patients with different cancers but the same biomarker with the same drug
- Research Gate: This diagram illustrates the difference between umbrella and basket trials
Tumor Agnostic Drugs and Trials
- Roche (video): Tumor agnostic means looking at the features of the cancer cells regardless of where in the body the cancer originated
- American Society of Clinical Oncology: Tumor-agnostic drugs are often studied in basket trials
MBC Clinical Trials
- Metastatic Trial Search: Tumor Agnostic or Solid Tumor Trials
Last Modified on April 1, 2024