All about Basket and Umbrella Trials - Metastatic Breast Cancer Trial Talk

Inside Clinical Trials

Basket trials and umbrella trials were created to help researchers study how tumors respond to targeted therapies.

Basket trials, also known as bucket trials, enroll patients whose tumors have a specific genetic mutation, regardless of where their cancer started.

Umbrella trials enroll patients with one type of cancer and have many different treatment arms. Patients are assigned to a specific arm based on the biomarkers seen in their tumor.

The articles below explain the goals of these trials. They also discuss potential challenges and concerns.

You can find all the basket trials enrolling breast cancer patients from

Understand Basket and Umbrella Trials

Basket and Umbrella Trials: Past and Now

Basket Trials: Advantages, Challenges and Opportunities

Current Basket Trials:

Last Modified on April 7, 2021



for past articles or specific information.