What is a Biomarker and How are Biomarkers Used in Clinical Trials? - Metastatic Breast Cancer Trial Talk

Inside Clinical Trials

Biomarkers are genes, molecules, or other features present in a person, including in a person’s tumor, that tell doctors something about a person’s health condition. Biomarkers in MBC include the estrogen receptor (ER), progesterone receptor (PR), and HER2, as well as mutations in genes such as ESR1 and PIK3CA. In MBC, biomarkers can predict how likely the cancer is to progress and may also help doctors and patients select the right treatment.

Some clinical trials are testing whether a specific biomarker is useful and in what groups of patients. In other clinical trials, biomarkers that were shown to be useful in previous studies are used as eligibility criteria for participation in a trial.

Read below to learn more about what biomarkers are and how they are used in clinical trials.

Last Modified on April 10, 2024



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