Adoptive cell therapies (ACTs) are a type of immunotherapy made from a patient’s own immune system. ACTs are made by removing T cells from the patient, growing large numbers of the T cells in a lab, and then putting the T cells back into the patient’s body. Types of adoptive cell therapy include CAR T-cell therapy, TIL therapy, NK cell therapy, and others. While adoptive cell therapies have succeeded in treating some blood cancers like lymphoma, so far, ACTs have not been as effective in treating solid tumors like breast cancer.
Read below to learn more about how ACTs are made, current progress and obstacles to using ACTs effectively in solid cancers, and clinical trials studying ACTs in people with metastatic breast cancer.
Adoptive Cell Therapy
- NCI Dictionary of Cancer Terms Adoptive Cell Therapy
- Cancer Research Institute Adoptive Cell Therapy
- ASCO Educational Book Adoptive Cellular Therapy for Solid Tumors
- American Cancer Society Journal Cancer: Adoptive T Cell Therapy: An Overview of Obstacles and Opportunities
Clinical Trials for Adoptive Cell Therapies
- Metastatic Trial Search Trials that Include ACT