What Are Master Protocols? - Metastatic Breast Cancer Trial Talk

Inside Clinical Trials

Master protocols are clinical trials that are specifically designed to allow researchers to study several molecular markers and targeted therapies simultaneously. These protocols also allow researchers to introduce new therapies into a trial that is already underway.

Researchers are still learning the best way to design these protocols and choose the proper statistical methods for evaluating their findings. Here you can read about how master protocols are being used in breast cancer and other clinical trials.

Want to learn more? The February issue of MTT discussed two types of master protocols: basket trials and umbrella trials.

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