MBC RESEARCH NEWS Update on CDK Inhibitors

August 2018

Update on CDK Inhibitors

Between February 2016 and March 2017 three CDK 4/6 inhibitors—palbociclib (Ibrance®), ribociclib (Kisqali®), and abemaciclib (Verzenio)—were approved for treating patients with hormone receptor (HR)-positive, HER2-negative metastatic breast cancer. Studies have found the three drugs to be equally effective, although their side effects can differ.

Below you will find an article on how these drugs work, an interview with breast cancer expert Dr. Hope Rugo on their use in metastatic breast cancer, and detailed information from Susan G. Komen on the trials and findings that led these three drugs to be approved. We’ve also included a piece on managing side effects as well as an article from Living Beyond Breast Cancer that profiles three women on these drugs and addresses treatment costs.

And last but not least, you can link directly to all trials for CDK inhibitors currently listed on BreastCancerTrials.org.

*To read this article, you will need to be or become a Medscape member. It’s free to sign up.

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